| City | Region | Population | Latitude | Longitude |
|---|---|---|---|---|
| Khairpur Tāmewah | Punjab | 30,967 | 29.5813900 | 72.2380400 |
| Khārān | Balochistān | 30,841 | 28.5845900 | 65.4150100 |
| Mehar | Sindh | 30,429 | 27.1802700 | 67.8205100 |
| Khāngāh Dogrān | Punjab | 30,314 | 31.8329400 | 73.6221300 |
| Khairpur Nathan Shāh | Sindh | 30,286 | 27.0906400 | 67.7348900 |
| Dīr | Khyber Pakhtunkhwa | 29,869 | 35.2074000 | 71.8768000 |
| Ghauspur | Sindh | 29,767 | 28.1388200 | 69.0824500 |
| Tangi | Khyber Pakhtunkhwa | 29,444 | 34.3009000 | 71.6523800 |
| Utmānzai | Khyber Pakhtunkhwa | 29,423 | 34.1877500 | 71.7627400 |
| Tāl | Khyber Pakhtunkhwa | 29,331 | 35.4790800 | 72.2438500 |
| Minchīanabād | Punjab | 29,253 | 30.1635600 | 73.5685800 |
| Garh Mahārāja | Punjab | 29,153 | 30.8338300 | 71.9049100 |
| Jahāniān Shāh | Punjab | 29,095 | 31.8054100 | 72.2774000 |
| Mastung | Balochistān | 29,082 | 29.7996600 | 66.8455300 |
| Mānānwāla | Punjab | 28,432 | 31.5880300 | 73.6892700 |
| Fāzilpur | Punjab | 28,213 | 32.1762900 | 75.0658300 |
| Talamba | Punjab | 28,151 | 30.5269300 | 72.2407900 |
| Kunjāh | Punjab | 28,103 | 32.5298200 | 73.9748600 |
| Jhāwāriān | Punjab | 27,893 | 32.3619200 | 72.6227500 |
| Nasīrābād | Sindh | 27,809 | 27.3813700 | 67.9164400 |
| Nushki | Balochistān | 27,680 | 29.5521800 | 66.0228800 |
| Sīta Road | Sindh | 27,587 | 27.0333300 | 67.8500000 |
| Dijkot | Punjab | 27,469 | 31.2173500 | 72.9962100 |
| Sillānwāli | Punjab | 27,023 | 31.8253900 | 72.5406400 |
| Kandiāro | Sindh | 26,807 | 27.0591800 | 68.2102200 |
| Zaida | Khyber Pakhtunkhwa | 26,787 | 34.0595000 | 72.4669000 |
| Kunri | Sindh | 26,773 | 25.1787400 | 69.5657200 |
| Kalāt | Balochistān | 26,701 | 29.0266300 | 66.5936100 |
| Dāūd Khel | Punjab | 26,395 | 32.8753300 | 71.5711800 |
| Mitha Tiwāna | Punjab | 26,390 | 32.2454000 | 72.1061500 |
| Hazro City | Punjab | 26,309 | 33.9099000 | 72.4917900 |
| Dūnga Būnga | Punjab | 25,893 | 29.7497500 | 73.2429400 |
| Amangarh | Khyber Pakhtunkhwa | 25,723 | 34.0058400 | 71.9297100 |
| Karor | Punjab | 25,634 | 31.2246000 | 70.9515300 |
| Kot Diji | Sindh | 25,616 | 27.3427200 | 68.7083400 |
| Kalūr Kot | Punjab | 25,574 | 32.1551200 | 71.2663100 |
| Murree | Punjab | 25,247 | 33.9083600 | 73.3903000 |
| Faqīrwāli | Punjab | 25,186 | 29.4679900 | 73.0348900 |
| Ahmadpur Siāl | Punjab | 24,889 | 30.6779100 | 71.7434400 |
| Phālia | Punjab | 24,789 | 32.4310400 | 73.5790000 |
| Yazman | Punjab | 24,580 | 29.1212200 | 71.7445900 |
| Rāja Jang | Punjab | 24,407 | 31.2207800 | 74.2548300 |
| Chak Five Hundred Seventy-five | Punjab | 24,295 | 31.5451400 | 73.8289100 |
| Pishin | Balochistān | 24,239 | 30.5817600 | 66.9940600 |
| Chak One Hundred Twenty Nine Left | Punjab | 24,053 | 30.4291900 | 73.0452200 |
| Chawinda | Punjab | 23,599 | 32.3443400 | 74.7050700 |
| Ubauro | Sindh | 23,462 | 28.1642900 | 69.7311400 |
| Mithi | Sindh | 23,431 | 24.7370100 | 69.7970700 |
| Akora | Khyber Pakhtunkhwa | 23,288 | 34.0033700 | 72.1256100 |
| Zafarwāl | Punjab | 23,078 | 32.3446400 | 74.8999000 |
| Kot Samāba | Punjab | 22,953 | 28.5520700 | 70.4683700 |
| Eminābād | Punjab | 22,679 | 32.0423700 | 74.2599600 |
| Kahuta | Punjab | 22,551 | 33.5918300 | 73.3873600 |
| Rānīpur | Sindh | 22,495 | 27.2879200 | 68.5050500 |
| Kulāchi | Khyber Pakhtunkhwa | 22,376 | 31.9305800 | 70.4595900 |
| Khānpur | Sindh | 22,273 | 27.8435800 | 69.4137300 |
| Hingorja | Sindh | 22,263 | 27.2108800 | 68.4159800 |
| Naukot | Sindh | 22,081 | 24.8582200 | 69.4015300 |
| Pind Dādan Khān | Punjab | 22,001 | 32.5866200 | 73.0445600 |
| Kanganpur | Punjab | 21,788 | 30.7646800 | 74.1228600 |
| Farūka | Punjab | 21,747 | 31.8864200 | 72.4136200 |
| Kotli Lohārān | Punjab | 21,463 | 32.5883000 | 74.4932100 |
| Shāhpur Chākar | Sindh | 21,446 | 26.1541100 | 68.6501300 |
| Talhār | Sindh | 21,154 | 24.8833300 | 68.8166700 |
| Pad Īdan | Sindh | 20,919 | 26.7747500 | 68.3019700 |
| Kot Ghulām Muhammad | Punjab | 20,897 | 32.3331100 | 74.5469400 |
| Qādirpur Rān | Punjab | 20,407 | 30.2918400 | 71.6716400 |
| Bela | Balochistān | 20,119 | 26.2271800 | 66.3117800 |
| Surkhpur | Punjab | 20,000 | 32.7166700 | 74.4500000 |
| Dhoro Naro | Sindh | 19,907 | 25.5048400 | 69.5709000 |
| Khāngarh | Punjab | 19,698 | 29.9144600 | 71.1606700 |
| Sarāi Naurang | Khyber Pakhtunkhwa | 19,694 | 32.8258100 | 70.7810700 |
| Ghāro | Sindh | 19,524 | 24.7418200 | 67.5853400 |
| Bhit Shāh | Sindh | 19,325 | 25.8056500 | 68.4914300 |
| Matiāri | Sindh | 18,929 | 25.5970900 | 68.4467000 |
| Dhanot | Punjab | 18,729 | 29.5799100 | 71.7521300 |
| Wārāh | Sindh | 18,724 | 27.4480500 | 67.7965400 |
| Lāchi | Khyber Pakhtunkhwa | 18,537 | 33.3829100 | 71.3373300 |
| Baddomalhi | Punjab | 18,435 | 31.9904200 | 74.6641000 |
| Jand | Punjab | 18,170 | 33.4298500 | 72.0192800 |
| Chak Two Hundred Forty-nine Thal Development Authority | Punjab | 18,126 | 31.1777200 | 71.2048000 |
| Dera Bugti | Balochistān | 18,120 | 29.0361900 | 69.1584900 |
| Thāru Shāh | Sindh | 17,698 | 26.9423000 | 68.1175900 |
| Naushahro Fīroz | Sindh | 17,631 | 26.8401000 | 68.1226500 |
| Dājal | Punjab | 17,630 | 29.5576900 | 70.3761400 |
| Daur | Sindh | 17,577 | 26.4552800 | 68.3183500 |
| Bhopālwāla | Punjab | 17,341 | 32.4296800 | 74.3635000 |
| Paharpur | Khyber Pakhtunkhwa | 17,294 | 32.1050200 | 70.9705500 |
| Bhān | Sindh | 16,961 | 26.5583100 | 67.7213900 |
| Mach | Balochistān | 16,930 | 29.8637100 | 67.3297900 |
| Goth Rādhan | Sindh | 16,786 | 27.1984600 | 67.9534800 |
| Uthal | Balochistān | 16,483 | 25.8072200 | 66.6219400 |
| Kāleke Mandi | Punjab | 16,361 | 31.9759700 | 73.5999900 |
| Jīwani | Balochistān | 16,322 | 25.0485200 | 61.7457300 |
| Johi | Sindh | 16,311 | 26.6922500 | 67.6143100 |
| Chhor | Sindh | 16,301 | 25.5126000 | 69.7843700 |
| Mangla | Punjab | 16,264 | 31.8930600 | 72.3816700 |
| Bhawāna | Punjab | 16,218 | 31.5688400 | 72.6491700 |
| Shahr Sultān | Punjab | 16,166 | 29.5751700 | 71.0220900 |
| Jhol | Sindh | 16,067 | 25.9550700 | 68.8882100 |