| City | Region | Population | Latitude | Longitude |
|---|---|---|---|---|
| Santo Domingo | Nacional | 2,201,941 | 18.5001200 | -69.9885700 |
| Santiago de los Caballeros | Santiago | 1,200,000 | 19.4517000 | -70.6970300 |
| Santo Domingo Oeste | Santo Domingo | 701,269 | 18.5000000 | -70.0000000 |
| Santo Domingo Este | Santo Domingo | 700,000 | 18.4884700 | -69.8570700 |
| San Pedro de Macorís | San Pedro de Macorís | 217,899 | 18.4615600 | -69.2971800 |
| La Romana | La Romana | 208,437 | 18.4273300 | -68.9728500 |
| Bella Vista | Nacional | 175,683 | 18.4553900 | -69.9454000 |
| San Cristóbal | San Cristóbal | 154,040 | 18.4166700 | -70.1000000 |
| Puerto Plata | Puerto Plata | 146,000 | 19.7934400 | -70.6884000 |
| San Francisco de Macorís | Duarte | 124,763 | 19.3009900 | -70.2525900 |
| Salvaleón de Higüey | La Altagracia | 123,787 | 18.6150100 | -68.7079800 |
| Concepción de la Vega | La Vega | 102,426 | 19.2220700 | -70.5295600 |
| Punta Cana | La Altagracia | 100,023 | 18.5818200 | -68.4043100 |
| Santa Cruz de Barahona | Barahona | 77,160 | 18.2085400 | -71.1007700 |
| Bonao | Monseñor Nouel | 73,269 | 18.9368700 | -70.4092300 |
| San Juan | San Juan | 72,950 | 18.8058800 | -71.2299100 |
| Bajos de Haina | San Cristóbal | 66,784 | 18.4153800 | -70.0331700 |
| Baní | Peravia | 66,709 | 18.2796400 | -70.3318500 |
| Moca | Espaillat | 61,834 | 19.3935200 | -70.5259800 |
| Azua | Azua | 59,139 | 18.4531900 | -70.7349000 |
| Villa Francisca | Nacional | 50,185 | 18.4827800 | -69.8891400 |
| Mao | Valverde | 48,297 | 19.5518600 | -71.0781300 |
| Boca Chica | Santo Domingo | 46,300 | 18.4500000 | -69.6000000 |
| Salcedo | Hermanas Mirabal | 45,299 | 19.3776200 | -70.4176200 |
| Esperanza | Valverde | 42,169 | 19.5846900 | -70.9848900 |
| Cotuí | Sánchez Ramírez | 41,641 | 19.0527200 | -70.1493900 |
| Villa Altagracia | San Cristóbal | 40,027 | 18.6729700 | -70.1709500 |
| Hato Mayor del Rey | Hato Mayor | 35,999 | 18.7627800 | -69.2568100 |
| Nagua | María Trinidad Sánchez | 33,862 | 19.3832000 | -69.8474000 |
| Villa Bisonó | Santiago | 33,137 | 19.5637800 | -70.8758200 |
| Jarabacoa | La Vega | 29,983 | 19.1168300 | -70.6359500 |
| Constanza | La Vega | 29,481 | 18.9091900 | -70.7449900 |
| Villa Consuelo | Nacional | 28,621 | 18.4833300 | -69.9000000 |
| Santa Cruz de El Seibo | El Seíbo | 23,547 | 18.7655900 | -69.0388600 |
| Tamboril | Santiago | 23,304 | 19.4853800 | -70.6110400 |
| Las Matas de Farfán | San Juan | 21,802 | 18.8730900 | -71.5165600 |
| San José de Ocoa | San José de Ocoa | 21,148 | 18.5466100 | -70.5063100 |
| Bayaguana | Monte Plata | 21,055 | 18.7503100 | -69.6352500 |
| Río Grande | Puerto Plata | 20,154 | 19.6666700 | -70.7666700 |
| Ciudad Nueva | Nacional | 18,756 | 18.4670700 | -69.8933900 |
| Neiba | Baoruco | 18,670 | 18.4813700 | -71.4196500 |
| Quisqueya | San Pedro de Macorís | 17,694 | 18.5554200 | -69.4081400 |
| San Fernando de Monte Cristi | Monte Cristi | 17,001 | 19.8482600 | -71.6459700 |
| Sabana Grande de Boyá | Monte Plata | 16,834 | 18.9449800 | -69.7933100 |
| Dajabón | Dajabón | 16,398 | 19.5487800 | -71.7082900 |
| Sabaneta | Santiago Rodríguez | 16,380 | 19.4779300 | -71.3412500 |
| Monte Plata | Monte Plata | 15,532 | 18.8070000 | -69.7839900 |
| Cristo Rey | Nacional | 14,325 | 18.5000000 | -69.9333300 |
| Sabana de La Mar | Hato Mayor | 13,977 | 19.0593400 | -69.3884300 |
| San Carlos | Nacional | 13,456 | 18.4833300 | -69.9000000 |
| Duvergé | Independencia | 13,405 | 18.3783900 | -71.5246900 |
| Cambita Garabitos | San Cristóbal | 13,382 | 18.4545800 | -70.1990700 |
| La Julia | Nacional | 12,575 | 18.4666700 | -69.9333300 |
| Cabral | Barahona | 12,303 | 18.2500000 | -71.2166700 |
| Comendador | Elías Piña | 12,070 | 18.8775000 | -71.7027800 |
| Salsipuedes | Hermanas Mirabal | 11,675 | 19.4055200 | -70.3798500 |
| Villa Vásquez | Monte Cristi | 11,642 | 19.7411000 | -71.4464000 |
| Yamasá | Monte Plata | 11,595 | 18.7731500 | -70.0258300 |
| San Gregorio de Nigua | San Cristóbal | 11,542 | 18.3833300 | -70.0833300 |
| Samaná | Samaná | 11,432 | 19.2056100 | -69.3368500 |
| Sánchez | Samaná | 11,365 | 19.2281000 | -69.6137000 |
| Pedernales | Pedernales | 11,072 | 18.0383800 | -71.7440300 |
| Vicente Noble | Barahona | 11,060 | 18.3844300 | -71.1800900 |
| Sabana Yegua | Azua | 10,624 | 18.7166700 | -71.0166700 |
| La Agustina | Nacional | 10,457 | 18.5000000 | -69.9333300 |
| Las Matas de Santa Cruz | Monte Cristi | 10,218 | 19.6711900 | -71.5047100 |
| Villa González | Santiago | 10,177 | 19.5405700 | -70.7885300 |
| Fantino | Sánchez Ramírez | 10,024 | 19.1214800 | -70.2997200 |
| San José de Las Matas | Santiago | 9,853 | 19.3391500 | -70.9381900 |
| Las Guáranas | Duarte | 9,586 | 19.1931000 | -70.2083500 |
| Pimentel | Duarte | 9,550 | 19.1841600 | -70.1088400 |
| Miches | El Seíbo | 9,273 | 18.9836400 | -69.0476000 |
| Villa Jaragua | Baoruco | 9,248 | 18.4907700 | -71.4837700 |
| Río San Juan | María Trinidad Sánchez | 8,983 | 19.6438500 | -70.0763500 |
| Ensanche Luperón | Nacional | 8,576 | 18.5000000 | -69.9000000 |
| Piedra Blanca | Monseñor Nouel | 8,531 | 18.8443100 | -70.3168800 |
| Padre Las Casas | Azua | 8,485 | 18.7317200 | -70.9391700 |
| Imbert | Puerto Plata | 8,024 | 19.7537100 | -70.8290600 |
| Las Terrenas | Samaná | 7,713 | 19.3110200 | -69.5428000 |
| Laguna Salada | Valverde | 7,601 | 19.6504300 | -71.0842900 |
| Tenares | Hermanas Mirabal | 7,390 | 19.3743900 | -70.3508700 |
| Peralta | Azua | 7,236 | 18.5816400 | -70.7702900 |
| El Factor | María Trinidad Sánchez | 7,014 | 19.3183400 | -69.8882700 |
| Paya | Peravia | 6,916 | 18.2619600 | -70.2956000 |
| Loma de Cabrera | Dajabón | 6,679 | 19.4333300 | -71.6000000 |
| Monción | Santiago Rodríguez | 6,625 | 19.4108300 | -71.1525700 |
| Jimaní | Independencia | 6,567 | 18.4916900 | -71.8502200 |
| Nizao | Peravia | 6,530 | 18.2469700 | -70.2105300 |
| Gaspar Hernández | Espaillat | 6,506 | 19.6274800 | -70.2777200 |
| Paraíso | Barahona | 6,490 | 17.9917200 | -71.1652600 |
| Licey al Medio | Santiago | 6,435 | 19.4333300 | -70.6000000 |
| Tamayo | Baoruco | 6,429 | 18.3947000 | -71.2029000 |
| Castillo | Duarte | 6,328 | 19.2082400 | -70.0272600 |
| Jima Abajo | La Vega | 6,299 | 19.1329200 | -70.3760700 |
| Guaymate | La Romana | 6,224 | 18.5879300 | -68.9786700 |
| Otra Banda | La Altagracia | 6,071 | 18.6501700 | -68.6628100 |
| Galván | Baoruco | 6,027 | 18.5022800 | -71.3427100 |
| Rincón | La Vega | 5,909 | 19.1193800 | -70.4063200 |
| Veragua Arriba | Espaillat | 5,858 | 19.5833300 | -70.3333300 |
| Villa Riva | Duarte | 5,700 | 19.1806900 | -69.9131900 |