| City | Region | Population | Latitude | Longitude |
|---|---|---|---|---|
| Guayaquil | Guayas | 1,952,029 | -2.2058400 | -79.9079500 |
| Quito | Pichincha | 1,399,814 | -0.2298500 | -78.5249500 |
| Cuenca | Azuay | 276,964 | -2.9005500 | -79.0045300 |
| Santo Domingo de los Colorados | Santo Domingo de los Tsáchilas | 200,421 | -0.2530500 | -79.1753600 |
| Machala | El Oro | 198,123 | -3.2586100 | -79.9605300 |
| Manta | Manabí | 183,166 | -0.9621200 | -80.7127100 |
| Portoviejo | Manabí | 170,326 | -1.0545800 | -80.4544500 |
| Durán | Guayas | 167,784 | -2.1757900 | -79.8551900 |
| Esmeraldas | Esmeraldas | 165,216 | 0.9592000 | -79.6539700 |
| Ambato | Tungurahua | 154,369 | -1.2490800 | -78.6167500 |
| Tutamandahostel | Pichincha | 140,000 | -0.1972700 | -78.4975000 |
| Milagro | Guayas | 133,508 | -2.1340400 | -79.5941500 |
| Ibarra | Imbabura | 132,977 | 0.3517100 | -78.1223300 |
| Riobamba | Chimborazo | 124,478 | -1.6709800 | -78.6471200 |
| Quevedo | Los Ríos | 119,436 | -1.0286300 | -79.4635200 |
| Loja | Loja | 117,796 | -3.9931300 | -79.2042200 |
| Tulcán | Carchi | 86,498 | 0.8118700 | -77.7172700 |
| Babahoyo | Los Ríos | 76,279 | -1.8021700 | -79.5344300 |
| La Libertad | Guayas | 75,881 | -2.2330000 | -80.9103900 |
| Latacunga | Cotopaxi | 51,717 | -0.9352100 | -78.6155400 |
| Velasco Ibarra | Guayas | 48,754 | -1.0437600 | -79.6383700 |
| Puerto Francisco de Orellana | Orellana | 48,144 | -0.4664500 | -76.9871900 |
| Ventanas | Los Ríos | 46,708 | -1.4415800 | -79.4594300 |
| Pasaje | El Oro | 44,860 | -3.3256100 | -79.8069700 |
| Chone | Manabí | 44,751 | -0.6981900 | -80.0936100 |
| Salinas | Santa Elena | 43,862 | -2.2145200 | -80.9515100 |
| Santa Elena | Santa Elena | 42,214 | -2.2262200 | -80.8587300 |
| Rosa Zarate | Esmeraldas | 42,121 | 0.3277900 | -79.4740700 |
| Santa Rosa | El Oro | 41,816 | -3.4488200 | -79.9595200 |
| Balzar | Guayas | 40,115 | -1.3650100 | -79.9049400 |
| Huaquillas | El Oro | 39,757 | -3.4752300 | -80.2308400 |
| Bahía de Caráquez | Manabí | 37,056 | -0.5979200 | -80.4236700 |
| La Troncal | Cañar | 36,353 | -2.4235500 | -79.3397700 |
| Jipijapa | Manabí | 35,901 | -1.3487200 | -80.5787500 |
| Azogues | Cañar | 34,877 | -2.7396900 | -78.8486000 |
| Naranjito | Guayas | 34,206 | -2.1667100 | -79.4654000 |
| Vinces | Los Ríos | 32,497 | -1.5561100 | -79.7519100 |
| Otavalo | Imbabura | 32,330 | 0.2345700 | -78.2624800 |
| El Triunfo | Guayas | 32,282 | -1.9333300 | -79.9666700 |
| Naranjal | Guayas | 32,045 | -2.6736400 | -79.6183000 |
| Playas | Guayas | 30,564 | -2.6319900 | -80.3880800 |
| Yaguachi Nuevo | Guayas | 27,947 | -2.0968000 | -79.6948500 |
| Cayambe | Pichincha | 26,582 | 0.0408400 | -78.1452400 |
| Machachi | Pichincha | 25,742 | -0.5101100 | -78.5671200 |
| Puyo | Pastaza | 24,881 | -1.4836900 | -78.0025700 |
| Nueva Loja | Sucumbios | 24,211 | 0.0860000 | -76.8952800 |
| Samborondón | Guayas | 24,118 | -1.9627600 | -79.7240200 |
| Macas | Morona-Santiago | 23,687 | -2.3086800 | -78.1113500 |
| Pedro Carbo | Guayas | 23,372 | -1.8156300 | -80.2330900 |
| Guaranda | Bolívar | 22,199 | -1.5926300 | -79.0009800 |
| Boca Suno | Orellana | 20,313 | -0.6983200 | -77.1408300 |
| San Lorenzo de Esmeraldas | Esmeraldas | 20,209 | 1.2862600 | -78.8351400 |
| Catamayo | Loja | 18,565 | -3.9865200 | -79.3591200 |
| Montecristi | Manabí | 18,351 | -1.0457600 | -80.6588900 |
| Atuntaqui | Imbabura | 17,456 | 0.3324700 | -78.2137100 |
| Calceta | Manabí | 17,286 | -0.8458200 | -80.1638900 |
| Tena | Napo | 17,172 | -0.9938000 | -77.8128600 |
| Gualaceo | Azuay | 17,122 | -2.8926400 | -78.7781400 |
| Piñas | El Oro | 16,981 | -3.6810700 | -79.6808300 |
| Cariamanga | Loja | 16,862 | -4.3279600 | -79.5555400 |
| Pelileo | Tungurahua | 16,572 | -1.3299000 | -78.5434100 |
| La Maná | Cotopaxi | 16,450 | -0.9409400 | -79.2250600 |
| Pujilí | Cotopaxi | 16,168 | -0.9575900 | -78.6963600 |
| Montalvo | Los Ríos | 15,547 | -1.7900800 | -79.2875900 |
| Sucre | Manabí | 15,286 | -1.2797400 | -80.4188500 |
| Zamora | Zamora-Chinchipe | 15,276 | -4.0668500 | -78.9548800 |
| San Gabriel | Carchi | 15,112 | 0.5931800 | -77.8307800 |
| Tosagua | Manabí | 14,680 | -0.7867900 | -80.2347300 |
| Alausí | Chimborazo | 14,294 | -2.2032900 | -78.8471400 |
| Muisne | Esmeraldas | 13,393 | 0.6112900 | -80.0186300 |
| Macará | Loja | 13,035 | -4.3818100 | -79.9437000 |
| Santa Ana | Manabí | 12,833 | -1.2072600 | -80.3713200 |
| Guano | Chimborazo | 12,659 | -1.6078900 | -78.6310500 |
| Alfredo Baquerizo Moreno | Guayas | 12,617 | -1.9166700 | -79.5166700 |
| San Miguel | Bolívar | 12,575 | -1.7088400 | -79.0431100 |
| Santa Lucía | Guayas | 12,523 | -2.1833300 | -80.0000000 |
| Zaruma | El Oro | 12,505 | -3.6913200 | -79.6117400 |
| Baláo | Guayas | 12,205 | -2.9110000 | -79.8144100 |
| Valdez | Esmeraldas | 11,441 | 1.2491700 | -78.9830600 |
| Catacocha | Loja | 10,872 | -4.0497400 | -79.6494400 |
| San Miguel de Salcedo | Cotopaxi | 10,838 | -1.0454700 | -78.5906300 |
| Rocafuerte | Manabí | 10,274 | -0.9236000 | -80.4494600 |
| Yantzaza | Zamora-Chinchipe | 9,970 | -3.8326100 | -78.7607600 |
| Cañar | Cañar | 9,900 | -2.5606200 | -78.9394000 |
| Catarama | Los Ríos | 9,723 | -1.5750400 | -79.4599800 |
| Portovelo | El Oro | 9,708 | -3.7214500 | -79.6218700 |
| Baños | Tungurahua | 9,501 | -1.3969900 | -78.4228900 |
| Colimes | Guayas | 9,384 | -1.5455300 | -80.0116500 |
| Palestina | Guayas | 9,364 | -1.9370900 | -79.7139600 |
| Paján | Manabí | 9,183 | -1.5523800 | -80.4295800 |
| Junín | Manabí | 9,128 | -0.9277700 | -80.2058300 |
| Palenque | Los Ríos | 9,083 | -1.4379500 | -79.7564700 |
| Puerto Ayora | Galápagos | 8,996 | -0.7401800 | -90.3138000 |
| Puerto Bolivar | El Oro | 8,300 | -3.2664900 | -79.9974900 |
| Cotacachi | Imbabura | 8,238 | 0.3010700 | -78.2642800 |
| Lomas de Sargentillo | Guayas | 7,542 | -1.8833300 | -80.0833300 |
| Píllaro | Tungurahua | 7,462 | -1.1741400 | -78.5467600 |
| Sucúa | Morona-Santiago | 7,413 | -2.4586600 | -78.1717100 |
| Pimampiro | Imbabura | 7,408 | 0.3911600 | -77.9406800 |
| Archidona | Napo | 7,309 | -0.9095000 | -77.8077200 |