| City | Region | Population | Latitude | Longitude |
|---|---|---|---|---|
| San Andrés Xecul | Totonicapán | 12,133 | 14.9000000 | -91.4833300 |
| El Quetzal | San Marcos | 12,122 | 14.7666700 | -91.8166700 |
| Sacapulas | Quiché | 12,088 | 15.2880100 | -91.0891400 |
| Flores Costa Cuca | Quetzaltenango | 11,984 | 14.6323800 | -91.8634100 |
| Salcajá | Quetzaltenango | 11,966 | 14.8833300 | -91.4500000 |
| Cabricán | Quetzaltenango | 11,946 | 15.0748500 | -91.6480000 |
| San Juan Chamelco | Alta Verapaz | 11,944 | 15.4333300 | -90.3333300 |
| Almolonga | Quetzaltenango | 11,913 | 14.8166700 | -91.5000000 |
| Chajul | Quiché | 11,657 | 15.4852300 | -91.0352000 |
| Atescatempa | Jutiapa | 11,543 | 14.1744400 | -89.7425000 |
| Melchor de Mencos | Petén | 11,457 | 17.0660600 | -89.1522900 |
| Ciudad Tecún Umán | San Marcos | 11,432 | 14.6773700 | -92.1403900 |
| Nueva Concepción | Escuintla | 11,121 | 14.2000000 | -91.3000000 |
| San Juan Cotzal | Quiché | 11,046 | 15.4336800 | -91.0348100 |
| San Antonio Suchitepéquez | Suchitepeque | 10,951 | 14.5333300 | -91.4166700 |
| Soloma | Huehuetenango | 10,916 | 15.6584100 | -91.4299400 |
| Cuyotenango | Suchitepeque | 10,825 | 14.5333300 | -91.5666700 |
| Santa Catarina Mita | Jutiapa | 10,817 | 14.4500000 | -89.7500000 |
| Rabinal | Baja Verapaz | 10,737 | 15.1000000 | -90.4500000 |
| Dolores | Petén | 10,604 | 16.5141700 | -89.4158300 |
| Jalpatagua | Jutiapa | 10,469 | 14.1416700 | -90.0086100 |
| Pastores | Sacatepéquez | 10,393 | 14.5966700 | -90.7547200 |
| Monjas | Jalapa | 10,351 | 14.5000000 | -89.8666700 |
| San Agustín Acasaguastlán | El Progreso | 10,335 | 14.9500000 | -89.9666700 |
| San Luis Jilotepeque | Jalapa | 10,306 | 14.6500000 | -89.7333300 |
| Oratorio | Santa Rosa | 10,155 | 14.2280600 | -90.1758300 |
| Nueva Santa Rosa | Santa Rosa | 10,130 | 14.3811100 | -90.2761100 |
| Masagua | Escuintla | 10,045 | 14.2030600 | -90.8480600 |
| Zunil | Quetzaltenango | 9,986 | 14.7833300 | -91.4833300 |
| Huitán | Quetzaltenango | 9,958 | 15.0492000 | -91.6394400 |
| San Martín Jilotepeque | Chimaltenango | 9,846 | 14.7877800 | -90.7925000 |
| Cubulco | Baja Verapaz | 9,753 | 15.1333300 | -90.5833300 |
| San Pedro La Laguna | Sololá | 9,681 | 14.6929700 | -91.2720100 |
| Parramos | Chimaltenango | 9,613 | 14.6077800 | -90.8030600 |
| Santa Ana | Petén | 9,523 | 16.8000000 | -89.8333300 |
| Ocós | San Marcos | 9,463 | 14.5099800 | -92.1929800 |
| Zaragoza | Chimaltenango | 9,361 | 14.6544400 | -90.8894400 |
| Zacualpa | Quiché | 9,241 | 15.0833300 | -90.8333300 |
| San Cristóbal Cucho | San Marcos | 9,152 | 14.9000000 | -91.7833300 |
| Sayaxché | Petén | 9,100 | 16.5244600 | -90.1880100 |
| Tactic | Alta Verapaz | 8,999 | 15.3221800 | -90.3544800 |
| Samayac | Quetzaltenango | 8,994 | 14.5808400 | -91.4613500 |
| Casillas | Santa Rosa | 8,970 | 14.4222200 | -90.2441700 |
| Yepocapa | Chimaltenango | 8,961 | 14.5041700 | -90.9569400 |
| Estanzuela | Zacapa | 8,937 | 15.0000000 | -89.5666700 |
| Concepción Huista | Huehuetenango | 8,925 | 15.6237800 | -91.6652100 |
| San Felipe | Retalhuleu | 8,921 | 14.6166700 | -91.6000000 |
| Santo Domingo Xenacoj | Sacatepéquez | 8,791 | 14.6777800 | -90.6977800 |
| San Raimundo | Guatemala | 8,689 | 14.7647200 | -90.5955600 |
| La Libertad | Petén | 8,646 | 16.7885000 | -90.1169800 |
| Chiantla | Huehuetenango | 8,465 | 15.3548400 | -91.4580700 |
| San Miguel Dueñas | Sacatepéquez | 8,424 | 14.5238900 | -90.7983300 |
| Cunén | Quiché | 8,400 | 15.3362600 | -91.0277600 |
| Pajapita | San Marcos | 8,164 | 14.7215200 | -92.0352100 |
| Moyuta | Jutiapa | 8,145 | 14.0386100 | -90.0808300 |
| Nuevo Progreso | San Marcos | 8,113 | 14.8000000 | -91.9166700 |
| San Jerónimo | Baja Verapaz | 8,093 | 15.0603200 | -90.2405000 |
| Concepción Chiquirichapa | Quetzaltenango | 8,080 | 14.8500000 | -91.6166700 |
| San Luis Ixcán | Quiché | 7,850 | 15.7872200 | -91.0950000 |
| Santa Cruz Balanyá | Chimaltenango | 7,825 | 14.6872200 | -90.9150000 |
| San Antonio Aguas Calientes | Sacatepéquez | 7,811 | 14.5397200 | -90.7694400 |
| San Antonio La Paz | El Progreso | 7,781 | 14.7497200 | -90.2866700 |
| Champerico | Retalhuleu | 7,761 | 14.3000000 | -91.9166700 |
| Río Bravo | Suchitepeque | 7,568 | 14.4004200 | -91.3171300 |
| El Tumbador | San Marcos | 7,562 | 14.8666700 | -91.9333300 |
| San Miguel Sigüilá | Quetzaltenango | 7,551 | 14.9000000 | -91.6166700 |
| Mataquescuintla | Jalapa | 7,539 | 14.5291700 | -90.1841700 |
| Chahal Guatemala | Alta Verapaz | 7,465 | 15.7912200 | -89.6051800 |
| El Progreso | Jutiapa | 7,350 | 14.3500000 | -89.8500000 |
| San Andrés | Petén | 7,235 | 16.9666700 | -89.9166700 |
| San Vicente Pacaya | Escuintla | 7,162 | 14.4161100 | -90.6391700 |
| Chuarrancho | Guatemala | 7,149 | 14.8216700 | -90.5086100 |
| Santo Tomás La Unión | Suchitepeque | 7,081 | 14.6333300 | -91.3833300 |
| Guazacapán | Santa Rosa | 7,080 | 14.0741700 | -90.4166700 |
| Acatenango | Chimaltenango | 7,050 | 14.5519400 | -90.9422200 |
| Santa María Chiquimula | Totonicapán | 6,980 | 15.0299200 | -91.3292000 |
| San Carlos Sija | Quetzaltenango | 6,831 | 14.9833300 | -91.5500000 |
| San Luis | Petén | 6,776 | 16.1988900 | -89.4402800 |
| Taxisco | Santa Rosa | 6,518 | 14.0671900 | -90.4679100 |
| La Libertad | Huehuetenango | 6,439 | 15.5142100 | -91.8694400 |
| Tacaná | San Marcos | 6,438 | 15.2405800 | -92.0672100 |
| Teculután | Zacapa | 6,407 | 14.9833300 | -89.7166700 |
| San José Acatempa | Jutiapa | 6,367 | 14.2652800 | -90.1269400 |
| Santo Domingo Suchitepéquez | Suchitepeque | 6,270 | 14.4666700 | -91.4833300 |
| San Bartolomé Milpas Altas | Sacatepéquez | 6,261 | 14.6061100 | -90.6800000 |
| Santa Cruz Naranjo | Santa Rosa | 6,254 | 14.3880600 | -90.3697200 |
| San Pablo La Laguna | Sololá | 6,186 | 14.7166700 | -91.2666700 |
| El Asintal | Retalhuleu | 6,156 | 14.6000000 | -91.7333300 |
| Río Hondo | Zacapa | 5,997 | 15.0666700 | -89.5833300 |
| San José Poaquil | Chimaltenango | 5,987 | 14.8197200 | -90.9063900 |
| Santa Rosa de Lima | Santa Rosa | 5,984 | 14.3880600 | -90.2955600 |
| Santa Cruz Verapaz | Alta Verapaz | 5,843 | 15.3666700 | -90.4333300 |
| San Antonio Huista | Huehuetenango | 5,669 | 15.6501000 | -91.7716300 |
| Senahú | Alta Verapaz | 5,633 | 15.4000000 | -89.8333300 |
| Magdalena Milpas Altas | Sacatepéquez | 5,582 | 14.5452800 | -90.6752800 |
| Aguacatán | Huehuetenango | 5,572 | 15.3422200 | -91.3114100 |
| San Mateo | Quetzaltenango | 5,534 | 14.8666700 | -91.5833300 |
| San Bernardino | Suchitepeque | 5,501 | 14.5333300 | -91.4500000 |
| La Democracia | Escuintla | 5,479 | 14.2308300 | -90.9472200 |
| Purulhá | Baja Verapaz | 5,370 | 15.2666700 | -90.2000000 |