| City | Region | Population | Latitude | Longitude |
|---|---|---|---|---|
| Ciudad Acuña | Coahuila | 144,669 | 29.3232200 | -100.9521700 |
| Ciudad del Carmen | Campeche | 141,308 | 18.6459200 | -91.8299100 |
| San Luis Río Colorado | Sonora | 139,254 | 32.4561200 | -114.7718600 |
| Salamanca | Guanajuato | 138,614 | 20.5719600 | -101.1915400 |
| Chetumal | Quintana Roo | 134,412 | 18.5141300 | -88.3038100 |
| Córdoba | Veracruz | 134,403 | 18.8842000 | -96.9255900 |
| Túxpam de Rodríguez Cano | Veracruz | 134,394 | 20.9577700 | -97.4080500 |
| Garza García | Nuevo León | 130,646 | 25.6538400 | -100.3775800 |
| Manzanillo | Colima | 130,035 | 19.0522200 | -104.3158300 |
| San Cristóbal de las Casas | Chiapas | 128,996 | 16.7317600 | -92.6412600 |
| Colima | Colima | 127,235 | 19.2499700 | -103.7271400 |
| Zamora | Michoacán | 124,916 | 19.9855000 | -102.2838700 |
| Huixquilucan | México | 124,846 | 19.3598500 | -99.3501600 |
| San Pedro Garza Garcia | Nuevo León | 122,009 | 25.6571600 | -100.4026800 |
| Naucalpan de Juárez | México | 121,470 | 19.3969400 | -99.2766700 |
| Orizaba | Veracruz | 121,348 | 18.8519500 | -97.0995700 |
| Navojoa | Sonora | 120,000 | 27.0702800 | -109.4437200 |
| Zacatecas City | Zacatecas | 118,562 | 22.7684300 | -102.5814100 |
| San Juan del Río | Querétaro | 118,173 | 20.3888600 | -99.9957700 |
| Ciudad de Villa de Álvarez | Colima | 117,600 | 19.2672200 | -103.7377800 |
| Milpa Alta | Mexico City | 115,895 | 19.1925100 | -99.0231700 |
| Texcoco | México | 115,378 | 19.5119400 | -98.8829300 |
| Iguala de la Independencia | Guerrero | 112,106 | 18.3453600 | -99.5413000 |
| Ciudad Valles | San Luis Potosí | 109,504 | 21.9833300 | -99.0166700 |
| Fresnillo | Zacatecas | 105,488 | 23.1812600 | -102.8713600 |
| Matamoros | Coahuila | 104,024 | 25.5269900 | -103.2285000 |
| Tantoyuca | Veracruz | 103,610 | 21.3506400 | -98.2257000 |
| Guaymas | Sonora | 103,449 | 27.9192800 | -110.8975500 |
| Las Margaritas | Chiapas | 103,403 | 16.3126500 | -91.9810700 |
| Ciudad Delicias | Chihuahua | 102,969 | 28.1901300 | -105.4701200 |
| Tulancingo | Hidalgo | 102,383 | 20.0835500 | -98.3628800 |
| Parral | Chihuahua | 101,768 | 26.9302200 | -105.6664000 |
| Temapache | Veracruz | 101,558 | 21.0661100 | -97.6420700 |
| Ciudad Guzmán | Jalisco | 101,010 | 19.7046600 | -103.4617000 |
| Playa del Carmen | Quintana Roo | 100,383 | 20.6274000 | -87.0798700 |
| Martínez de la Torre | Veracruz | 100,377 | 20.0708200 | -97.0607800 |
| Colonia Lindavista | México | 100,000 | 19.4915600 | -99.1247500 |
| Apatzingán | Michoacán | 98,422 | 19.0886400 | -102.3570400 |
| Guadalupe | Zacatecas | 94,089 | 22.7475300 | -102.5187400 |
| San Juan Bautista | Oaxaca | 92,121 | 18.0883000 | -96.1253500 |
| Temixco | Morelos | 91,059 | 18.8525400 | -99.2253700 |
| Cuauhtémoc | Chihuahua | 90,835 | 28.4088400 | -106.8631900 |
| Hacienda Santa Fe | Jalisco | 86,935 | 20.5180600 | -103.3805600 |
| Atlixco | Puebla | 85,891 | 18.9081500 | -98.4361300 |
| Río Bravo | Tamaulipas | 85,481 | 25.9872900 | -98.0941400 |
| Cárdenas | Tabasco | 85,350 | 18.0013500 | -93.3755900 |
| Cuautitlán | México | 84,737 | 19.6705200 | -99.1798900 |
| Lagos de Moreno | Jalisco | 84,677 | 21.3566600 | -101.9376800 |
| Tlaxcala City | Tlaxcala | 84,670 | 19.3190500 | -98.1998200 |
| Chicoloapan | México | 84,440 | 19.4168700 | -98.9020200 |
| Lázaro Cárdenas | Michoacán | 84,001 | 17.9706600 | -102.2212400 |
| Tepatitlán de Morelos | Jalisco | 83,694 | 20.8169200 | -102.7634700 |
| Ocotlán | Jalisco | 81,527 | 20.3553000 | -102.7735800 |
| San Andrés Cholula | Puebla | 80,118 | 19.0514400 | -98.2952600 |
| Ciudad Mante | Tamaulipas | 79,981 | 22.7430400 | -98.9739000 |
| Comitán | Chiapas | 79,944 | 16.2447100 | -92.1342500 |
| Tecoman | Colima | 79,579 | 18.9167800 | -103.8778600 |
| Heróica Zitácuaro | Michoacán | 78,950 | 19.4361200 | -100.3573300 |
| Guanajuato City | Guanajuato | 78,364 | 21.0185800 | -101.2591000 |
| Agua Prieta | Sonora | 77,254 | 31.3307100 | -109.5487600 |
| Kanasín | Yucatán | 77,240 | 20.9348200 | -89.5587100 |
| Amozoc de Mota | Puebla | 77,106 | 19.0461100 | -98.0450000 |
| San Martin Texmelucan de Labastida | Puebla | 75,903 | 19.2843100 | -98.4388500 |
| Fuentes del Valle | México | 74,087 | 19.6325000 | -99.1386100 |
| San Miguel de Cozumel | Quintana Roo | 73,934 | 20.5003800 | -86.9427200 |
| Chiautla | México | 73,696 | 19.5489500 | -98.8823600 |
| Salina Cruz | Oaxaca | 73,648 | 16.1840500 | -95.2014300 |
| El Pueblito | Querétaro | 71,254 | 20.5397200 | -100.4413900 |
| Teziutlán | Puebla | 70,819 | 19.8173000 | -97.3599200 |
| La Piedad | Michoacán | 70,238 | 20.3423900 | -102.0305000 |
| San Miguel de Allende | Guanajuato | 69,811 | 20.9152800 | -100.7438900 |
| San Mateo Atenco | México | 68,602 | 19.2675700 | -99.5321400 |
| Guasave | Sinaloa | 68,449 | 25.5674500 | -108.4675600 |
| Cadereyta | Nuevo León | 67,994 | 25.5833300 | -99.9833300 |
| Matehuala | San Luis Potosí | 67,717 | 23.6482400 | -100.6433400 |
| Miramar | Tamaulipas | 67,689 | 22.3208500 | -97.8595000 |
| Juchitán de Zaragoza | Oaxaca | 67,637 | 16.4360300 | -95.0197500 |
| San Francisco del Rincón | Guanajuato | 66,949 | 21.0184300 | -101.8551500 |
| Rosarito | Baja California | 66,020 | 32.3604400 | -117.0464500 |
| Tultepec | México | 65,338 | 19.6850000 | -99.1280600 |
| Silao | Guanajuato | 65,195 | 20.9435600 | -101.4270300 |
| Ciudad Frontera | Coahuila | 64,976 | 26.9281400 | -101.4521200 |
| Lerdo | Coahuila | 63,530 | 25.5371800 | -103.5245600 |
| Santa Cruz Xoxocotlán | Oaxaca | 61,846 | 17.0295800 | -96.7351800 |
| Teoloyucan | México | 61,376 | 19.7442300 | -99.1811300 |
| San Salvador Tizatlalli | México | 61,367 | 19.2602800 | -99.5908300 |
| Zihuatanejo | Guerrero | 61,308 | 17.6434400 | -101.5521200 |
| Valle de Santiago | Guanajuato | 60,528 | 20.3914000 | -101.1922200 |
| Colonia Nativitas | Mexico City | 60,000 | 19.3811900 | -99.1368500 |
| Guamúchil | Sinaloa | 59,276 | 25.4587000 | -108.0773200 |
| Dolores Hidalgo Cuna de la Independencia Nacional | Guanajuato | 59,240 | 21.1561100 | -100.9325000 |
| Sahuayo de Morelos | Michoacán | 58,513 | 20.0585900 | -102.7157500 |
| Tecate | Baja California | 58,300 | 32.5671700 | -116.6250900 |
| Linares | Nuevo León | 57,731 | 24.8579800 | -99.5676800 |
| Cortazar | Guanajuato | 56,360 | 20.4836200 | -100.9623700 |
| Acámbaro | Guanajuato | 56,263 | 20.0308500 | -100.7219400 |
| San Andres Tuxtla | Veracruz | 55,697 | 18.4487000 | -95.2132700 |
| Ciudad Hidalgo | Michoacán | 54,993 | 19.6927000 | -100.5544500 |
| Altamira | Tamaulipas | 54,954 | 22.3921500 | -97.9386700 |
| San Miguel Zinacantepec | México | 54,220 | 19.2842800 | -99.7339400 |